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Bacteria typically have a one-point (the origin of replication) from which replication starts, whereas some archaea contain multiple replication origins.
The genes in prokaryotes are often organized in operons, and do not usually contain introns, unlike eukaryotes. Instead, their DNA is organized into a structure called the nucleoid.
His error was copied by others and it was not until 1956 that the true number, 46, was determined by Indonesia-born cytogeneticist Joe Hin Tjio.
Prokaryotic chromosomes have less sequence-based structure than eukaryotes.
Wilhelm Roux suggested that each chromosome carries a different genetic load.Before this happens, every chromosome is copied once (S phase), and the copy is joined to the original by a centromere, resulting either in an X-shaped structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends.The original chromosome and the copy are now called sister chromatids.During metaphase the X-shape structure is called a metaphase chromosome.In this highly condensed form chromosomes are easiest to distinguish and study.
Boveri influenced two generations of American cytologists: Edmund Beecher Wilson, Nettie Stevens, Walter Sutton and Theophilus Painter were all influenced by Boveri (Wilson, Stevens, and Painter actually worked with him).